Not available outside of the UK & Ireland.

Application

Neutralization Studies (see application references)

Biochem/physiol Actions

≥1 x 10⁵ neutralization units/ml

General description

Recognizes the ~20 kDa IFN-β protein. Note: 1 KU = 1000 neutralization units.

Rabbit polyclonal antibody supplied as diluted serum. Recognizes the ~20 kDa β-interferon protein.

This Anti-β-Interferon Rabbit pAb is validated for use in Neutralization Studies for the detection of β-Interferon.

Immunogen

recombinant, human β-interferon

Human

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Does not recognize α-interferon or γ-interferon by immunoblotting. Effectively neutralizes human β-interferon (see application references). One neutralization unit is the amount of diluted serum required to neutralize 1 unit of human interferon-β. One KU = 1,000 neutralization units. Variables associated with assay conditions will dictate the proper working dilution.

Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.Rubinstein, S., et al. 1981. J. Virol. 37, 755.

Packaging

20 ku in Plastic ampoule

Physical form

Serum diluted in PBS.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Standard Handling (A)