Not available outside of the UK & Ireland.
General description
Native apolipoprotein E from human plasma. A component of VLDL and a subclass of HDL. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation, cell growth, and differentiation. Present in normal plasma at concentrations of 50 µg/ml.
Native apolipoprotein E from human plasma. A component of VLDL and of a subclass of HDL. Present in normal plasma at concentrations of 50 µg/ml. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation and cell growth differentiation. Inhibits mitogen-induced T-lymphocyte proliferation and modulation of smooth muscle cell differentiation.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Kelly, M.E., et al. 1994. Cell Immunol. 159, 124.Mahley, R.W. 1988. Science 240, 622.Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.
Packaging
50 µg in Plastic ampoule
Please refer to vial label for lot-specific concentration.
Physical form
In 50 mM NH4HCO3, pH 8.0.
Preparation Note
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Warning
Toxicity: Standard Handling (A)
This product has met the following criteria: