Lincomycin hydrochloride, BioReagent, suitable for cell culture

Code: l2774-1mu D2-231

Not available outside of the UK & Ireland.

Application

Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. I...


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Not available outside of the UK & Ireland.

Application

Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It is produced by Streptomyces lincolnensis var. lincolnensis, and has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.

Biochem/physiol Actions

Mode of action: Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA.† Antimicrobial spectrum: Lincomycin hydrochloride is effective against gram-positive bacteria.

General description

Chemical structure: macrolide

Packaging

1000000, 5000000 units in glass bottle

Preparation Note

This product is soluble in water at 50 mg/mL, yielding a clear, colorless solution.

antibiotic activity spectrumGram-positive bacteria
colorwhite to yellow-white
InChI keyPOUMFISTNHIPTI-BOMBIWCESA-N
InChI1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1
mode of actionprotein synthesis | interferes
potency800-900 units per mg
product lineBioReagent
Quality Level200
SMILES stringCl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
solubilityH2O: 4 mL, clear, colorless to faintly yellow (200 mg + 4 mL H2O)
storage temp.2-8°C
technique(s)cell culture | mammalian: suitable
Code
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L2774-5MU
Lincomycin hydrochloride, BioReagent, suitable for cell culture

Unit:EACH
List Price: $403.10
Source:List Price
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Cas Number859-18-7
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