Tylosin solution, 8 mg/mL in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture

Code: t3397-20ml D2-231

Not available outside of the UK & Ireland.

Application

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus<...


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£26.30 20ML
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Not available outside of the UK & Ireland.

Application

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation.

Biochem/physiol Actions

Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and Mycoplasma gallisepticumandMycoplasma meleagridisinfections.

General description

Chemical structure: macrolide

Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Packaging

20ML

Preparation Note

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

antibiotic activity spectrummycoplasma, Gram-positive bacteria
colorcolorless to yellow
concentration8 mg/mL in 0.9% NaCl
formsolution
impuritiesendotoxin, tested
InChI keyICVKYYINQHWDLM-KBEWXLTPSA-N
InChI1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
mode of actionprotein synthesis | interferes
product lineBioReagent
Quality Level200
SMILES stringO[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)C=CC(C)=C[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
sterility0.1 µm filtered
storage condition(Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and keep upright to prevent leakage.)
storage temp.2-8°C
technique(s)cell culture | mammalian: suitable
Cas Number74610-55-2
This product has met the following criteria: