Losartan potassium, analytical standard

Code: 61188-100mg D2-231

Not available outside of the UK & Ireland.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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Your Price
$207.55 100MG
$249.06 inc. VAT

Not available outside of the UK & Ireland.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Losartan potassium may be used as an analytical reference standard for the quantification of the analyte in the following:Pharmaceutical formulations using reversed-phase high-performance liquid chromatography and UV-spectrophotometric techniques.Rat plasma using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique.

Biochem/physiol Actions

Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.

General description

Losartan potassium is an antihypertensive drug that is found to be an angiotensin II receptor type 1 blocker. It finds applications in reducing mechanical stress thereby having a control over the condition of cardiac hypertrophy.

Losartan potassium has long lasting effects, and its efficacy is generally increased, when combined with the diuretic co-active hydrochlorothiazide.

Packaging

100 mg in glass bottle

application(s)forensics and toxicologypharmaceutical (small molecule)veterinary
formpowder or crystals
Gene Informationhuman ... AGTR1(185)
impurities≤0.5% water
InChI keyOXCMYAYHXIHQOA-UHFFFAOYSA-N
InChI1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
Quality Level200
shelf lifelimited shelf life, expiry date on the label
SMILES stringCCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
technique(s)gas chromatography (GC): suitable, HPLC: suitable
Cas Number124750-99-8
This product has met the following criteria: