L-Ascorbic acid, reagent grade, crystalline

Code: a7506-100g D2-231

Not available outside of the UK & Ireland.

Application

L-Ascorbic acid has been used: as a chondrogenic medium component for culturing bone-derived mesenchymal stem cells (BMSCs)(149) as a reference standard in high-p...


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Your Price
$39.01 100G

Not available outside of the UK & Ireland.

Application

L-Ascorbic acid has been used: as a chondrogenic medium component for culturing bone-derived mesenchymal stem cells (BMSCs)(149) as a reference standard in high-performance liquid chromatography system (HPLC)(150) to test its effect on human gastric cancer GES-1 and AGS cells(151)

Biochem/physiol Actions

L-Ascorbic acid deficiency is associated with lack of L-gulono-1,4-lactone oxidase (GLO) enzyme. It elicits antioxidant functionality and gets oxidized to dehydroascorbate via ascorbyl radical intermediate. L-Ascorbic acid is essential for maintaining the redox balance. It is a cofactor for dopamine-β-hydroxylase and favors T cell proliferation, protects immune system and provides relief in common cold.

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Caution

May darken in storage.

General description

L-Ascorbic acid biosynthetic pathway varies in plants, animals and fungi. It is synthesized from L-gulono-1,4-lactone by the action of enzyme L-gulono-1,4-lactone oxidase (GLO).

Packaging

25, 100, 500 g in poly bottle

5 kg in poly drum

1 kg in poly bottle

assay≥98% ( with iodine, titration)
biological sourcesynthetic
colorwhite to slightly yellow
formcrystalline
Gene Informationhuman ... SLC23A2(9962)
gradereagent grade
InChI keyCIWBSHSKHKDKBQ-JLAZNSOCSA-N
InChI1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
mp190-194 °C (dec.)
pH1.0-2.5 (25 °C, 176 g/L in water)
Quality Level200
SMILES stringOC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
solubilitywater: soluble 50 mg/mL
storage temp.room temp
technique(s)cell culture | stem cell: suitable, HPLC: suitable
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Description
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A7506-1KG
Unit:1KG
List Price: $192.85
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A7506-25G
Unit:25G
List Price: $22.04
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A7506-500G
Unit:500G
List Price: $124.99
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A7506-5KG
Unit:5KG
List Price: $767.05
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Cas Number50-81-7
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