Capto™ L resin is designed for antibody fragment purification, when the fragment contains the kappa light chain.
- Suitable for the capture of a wide range of antibody fragments such as Fabs, dAbs, and single-chain fragment variable (scFv)
- High binding capacity, low ligand leakage, and selectivity for a broad range of antibody fragments reduces process time and amount of resin
- Enables a platform approach to antibody fragment purification
- Excellent productivity, process economy, and process design flexibility due to rigid matrix
- Hydrophilic base matrix ensures low levels of non-specific binding and low levels of host cell-derived impurities in the elution pool
- Fulfils industrial demands for security of supply, robust performance, and regulatory support
Capto™ L combines a rigid, high-flow agarose matrix with the immunoglobulin-binding recombinant protein L ligand, which has a strong affinity to the variable region of antibody kappa light chains.
This product has met the following criteria: