Not available outside of the UK & Ireland.

Application

Cyclophosphamide monohydrate has been used:to test its antitumor effect on TC-1 tumor cellsas a component of multidrug solution for isolation of resistant human burkitt lymphoma cell linein testing antitumor immunity in mouse tumor cell lines

Biochem/physiol Actions

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Features and Benefits

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General description

Cyclophosphamide (CYC) is a cytotoxic alkylating agent. It is activated by the cytochrome P-450 enzyme system in the liver. It has immunomodulatory functionality and inhibits humoral and cellular immunity.

Packaging

1, 5, 10, 25 g in glass bottle