Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide), PEG average Mn 5,000, PLGA Mn 55,000

Code: 764752-1g D2-231

Not available outside of the UK & Ireland.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

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Your Price
$504.70 1G
$605.64 inc. VAT

Not available outside of the UK & Ireland.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

Good biocompatibility, low immunogenicity and good degradability.Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

General description

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.

Packaging

1 g in glass bottle

degradation timeframe1-4 weeks
descriptiontypical PEG PDI ﹤ 1.1; overall PDI ﹤ 2.5
feed ratiolactide:glycolide 50:50
formpellets
mol wtPLGA Mn 55,000, PEG average Mn 5,000, average Mn 60,000 (total)
PDI﹤1.2
Quality Level100
storage temp.2-8°C
transition tempTm 254-259 °C, Tg 10 °C(lit.)
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