Researchers have discovered that DNA can adhere to the surface of certain plastic materials, particularly polypropylene, commonly used in PCR (polymerase chain reaction) plates. This finding has significant implications for scientific applications involving low reaction volumes, quantitative PCR (qPCR), and Next-Generation Sequencing (NGS) techniques, as DNA binding can negatively impact experimental results.
Arvensis, a prominent name in scientific equipment manufacturing, commissioned an independent analysis firm to conduct comprehensive DNA binding tests and compare their PCR plates to those of the leading global brands. The primary aim of this investigation was to determine whether there are notable differences in DNA binding characteristics among these renowned brands.
The research encompassed four sets of plates, each subject to rigorous evaluation of DNA retention on PCR plastics:
- Arvensis A-Frame® 96 Well PCR Plate (Item AFC-1041)
- Arvensis B-Frame® BIOCOMPOSITE 96 Well PCR Plate (Item BF-1001)
- Bio-Rad Hard-Shell® 96-Well PCR Plates (Item HSP-9601)
- Eppendorf twin.tec® PCR Plates LoBind® (Item 0030129504)
In summary, there was no difference found in DNA binding between Arvensis products and low binding products from leading brands. This highlights Arvensis’ commitment to quality and integrity, as they only offer plates made of low binding plastic as an integral feature of the regular line of products; not as a specialty item, and not at a higher price point.
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